Audit: QRS - Alpha-Lactalbumin for Health & Longevity

Audit conducted on 20/06/2026 02:23 using AI4L / Opus 4.8

Iterations

Summary

Items Count
Total 91
Passed 85
Failed 0
N/A 6
Pass Rate 100.00%
  • Total = Passed + Failed + N/A
  • Pass Rate = Passed / (Passed + Failed) × 100
  • N/A items are excluded from the pass rate calculation

1. General Rules

# Description Result Comments
1.1 Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. 🟢 All QRS content traces to the ER: at-a-glance to Conclusion, benefits/risks to their ER sections, protocol/time-to-effect, monitoring markers, and qualitative items.
1.2 Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. 🟢 Speculative risk “Theoretical serotonin excess” mirrors ER’s “theoretical” framing (ER line 234-236).
1.3 The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). 🟢 No strengthening or softening detected; tier placements preserved.
1.4 The QRS does not relabel an ER fact under a different decision category. 🟢 Contraindications, interactions, benefits, and risks all drawn from the matching ER sections.
1.5 PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. 🟢 The QRS introduces no PMIDs, NCT IDs, expert names, or brand names.
1.6 The QRS does not introduce new attributions. 🟢 No new attributions present.

2. Focus, Tone & Audience

# Description Result Comments
2.1 The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. 🟢 Objective, evidence-led tone matches the ER.
2.2 The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging 🟢 Maintained throughout.
2.3 The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor 🟢 Presents evidence, not directives.
2.4 The QRS avoids language that implies medical or clinical advice 🟢 No prescriptive advice; disclaimer present.
2.5 The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” 🟢 Descriptive framing used throughout.
2.6 The QRS never addresses “the reader” directly — it presents evidence, not guidance 🟢 No second-person address.
2.7 The QRS is written in plain language, avoiding unnecessary medical jargon 🟢 Plain language used; minimal jargon.
2.8 Information is presented in a concise and very compact manner 🟢 Compact card/cell format.
2.9 It DOES NOT address the reader directly 🟢 Confirmed; no “you”/”your”.
2.10 The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. 🟢 Framing reflects this audience.
2.11 The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. 🟢 Protocol/sourcing framing consistent.
2.12 The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. 🟢 Not general-population framed.
2.13 Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. 🟢 At-a-glance notes benefits fade in well-rested/resilient people, matching the population-dependent framing.
2.14 The document’s own voice frames usage in longevity terms, not “anti-aging”. Proper names that contain “anti-aging” are quoted verbatim. 🟢 No “anti-aging” usage.
2.15 The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language. Direct quotes from sources are exempt. 🟢 Formal terminology throughout.

3. Template Integrity

# Description Result Comments
3.1 The following labels and headings on the QRS are fixed and not modified: Card and section headings (“Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”); Gate headings (“Contraindications”, “Key Interactions”); Tier labels (“High”, “Medium”, “Low”, “Speculative”); Table column headers in Monitoring (“Marker”, “Target”, “Why”). 🟢 All fixed headings/labels intact.
3.2 All “” from the [qrs_template] are present in the the QRS. 🟢 All data-qrs-var spans present.
3.3 Spans that are not addressed in a checklist item are left unchanged 🟢 website= anchor spans (evidence_review, audit, full_review) unchanged.

4. Formatting

# Description Result Comments
4.1 When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” N/A No mapped ER section is empty; absent tiers use display:none per 12.5/13.5.
4.2 Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. 🟢 Protocol labels (Standard evening dose, Timing before sleep, Single versus split dosing) match ER bold labels.
4.3 Labels are not paraphrased, abbreviated, or invented. 🟢 Labels verbatim from ER.
4.4 The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. 🟢 No emoji indicators in rendered content.
4.5 The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. 🟢 Content condensed to one-page budget.

5. Metadata

# Description Result Comments
5.1 The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. 🟢 Metadata comment is first element (lines 2-14).
5.2 Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. 🟢 YAML delimited by — (lines 3 and 13).
5.3 The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. 🟢 Inside HTML comment; not rendered.
5.4 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 duration “00:02” quoted (contains colon); all others trimmed.
5.5 The filename of the source ER is stated as “er_filename: [er_filename]” 🟢 er_filename: alpha_lactalbumin_2026-0620-0126_Opus_ER.md
5.6 Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” 🟢 qrs_prompt_version: 26.5.18 matches QRS.md version.
5.7 Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” 🟢 qrs_creation_date: 2026-0620-0126
5.8 The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” 🟢 qrs_creator_ai_nickname: Opus
5.9 The nickname of the AI is just a single word model name without version, etc. 🟢 “Opus” is single word.
5.10 The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” 🟢 qrs_creator_ai_fullname: Opus 4.8
5.11 The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier 🟢 “Opus 4.8” — nickname plus version, no qualifier.
5.12 The filename of the document is stated as “qrs_filename: [filename of this document]” 🟢 qrs_filename: alpha_lactalbumin_2026-0620-0126_Opus_QRS.html
5.13 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Consistent and trimmed.

6. Page Title & Header

# Description Result Comments
6.1 [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet”. The [canonical_topic] is HTML-entity-encoded as needed. 🟢 “Alpha-Lactalbumin for Health & Longevity - Quick Reference Sheet”.
6.2 [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed. 🟢 “Alpha-Lactalbumin for Health & Longevity”.
6.3 [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] 🟢 06/20/2026 from 2026-0620.
6.4 [header_subline_model] is set to [qrs_creator_ai_fullname] 🟢 “Opus 4.8”.
6.5 No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. 🟢 Header carries only date, ER link, AI4L link, and model.

7. At-A-Glance Section

# Description Result Comments
7.1 [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section 🟢 Condenses the ER Conclusion (lines 402-404).
7.2 [at_a_glance] is no longer than 60 words 🟢 56 words.
7.3 Every fact in [at_a_glance] is supported by a distinct passage in the ER. 🟢 Tryptophan/serotonin, sleep onset, mood-under-stress, population-dependence, next-morning alertness, recovery, and cow’s-milk allergy risk all supported.
7.4 It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead 🟢 No acronyms (LNAA, tryptophan-to-LNAA, etc. omitted).
7.5 It DOES NOT cite specific trials (names, years, sample sizes, p-values) 🟢 No trials cited.
7.6 It DOES NOT cite effect sizes, relative risks, or statistical results 🟢 No statistics cited.

8. Contraindications

# Description Result Comments
8.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Derived from ER line 272.
8.2 [stop_items] represent the Contraindications from the ER 🟢 “Diagnosed cow’s milk protein allergy” — the sole ER contraindication.
8.3 Individual [stop_items] are formatted as <li></li> 🟢 Single <li> item.
8.4 Items are as concise as possible. No trailing explanations, elaborations, mechanistic rationale, attributions, citations, study details. No content after an em-dash, en-dash, or hyphen-dash. Just the key fact. 🟢 Concise, no trailing clauses.
8.5 Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible. 🟢 ER contraindication has no parenthetical qualifier to preserve.
8.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list. 🟢 No ranking notation in the contraindication.
8.7 If no [stop_items] are present the section is left empty N/A One stop item present (cow’s milk protein allergy); the “if no items” condition does not apply.

9. Key Interactions

# Description Result Comments
9.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Derived from ER lines 260-270.
9.2 [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications 🟢 Six interactions listed; the cow’s-milk-allergy contraindication is excluded.
9.3 Individual [caution_items] are formatted as <li></li> 🟢 Each item a separate <li>.
9.4 Items are as concise as possible. No trailing explanations, elaborations, mechanistic rationale, attributions, citations, study details. No content after an em-dash/en-dash/hyphen-dash. Just the key fact. 🟢 Trailing rationale stripped; concise.
9.5 Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible. 🟢 Example drug lists (SSRIs, SNRIs, MAOIs; OTC antihistamines, hypnotics; inositol forms) preserved.
9.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering), normalize the items to a plain comma-separated list. 🟢 No ranking notation present; lists are comma-separated.
9.7 If no [caution_items] are present the section is left empty N/A Six caution items present; the “if no items” condition does not apply.

10. Protocol

# Description Result Comments
10.1 The section is derived from the ER Protocol section 🟢 Derived from ER Therapeutic Protocol (lines 292-296).
10.2 The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section 🟢 Dose, timing before sleep, single-vs-split dosing.
10.3 If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible. N/A Three actionable aspects available; the “less than three” condition does not apply.
10.4 All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. 🟢 All three action cells fully populated from ER.

11. Time to Effect

# Description Result Comments
11.1 The three sets of [time] items cover the three most important time-to-effect aspects from the ER 🟢 Sleep onset, stress and mood, next-morning alertness.
11.2 The sets are picked and ordered by the magnitude of the related benefit 🟢 Sleep (Medium), stress/mood (Medium), next-morning alertness (Low).
11.3 If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible. N/A Three time-to-effect aspects available; the “less than three” condition does not apply.
11.4 All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. 🟢 All three time cells populated from ER Practical Considerations (line 343).
11.5 If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel N/A ER provides time-to-effect information; the “if no information” condition does not apply.

12. Benefits

# Description Result Comments
12.1 The section is derived from the ER Expected Benefits section 🟢 Derived from ER lines 134-183.
12.2 Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] 🟢 All four variables present.
12.3 Items are as concise as possible. No explanations, elaborations, effect sizes, qualifiers, attributions, citations, study details, mechanistic explanations. Just the key fact. 🟢 Benefit headings condensed without qualifiers.
12.4 Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 ER “(Adjunct in PCOS)” stripped from the metabolic/reproductive item.
12.5 If no items of a specific sub-section are present the respective is set to “display=none”, not filled with empty-state phrasing. 🟢 benefits_high set to display:none (no High benefits in ER).

13. Risks

# Description Result Comments
13.1 The section is derived from the ER Potential Risks & Side Effects section 🟢 Derived from ER lines 203-240.
13.2 Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] 🟢 All four variables present.
13.3 Items are as concise as possible. No explanations, elaborations, effect sizes, qualifiers, attributions, citations, study details, mechanistic explanations. Just the key fact. 🟢 Risk headings condensed without elaboration.
13.4 Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 No parenthetical detail carried through.
13.5 If no items of a specific sub-section are present the respective is set to “display=none”, not filled with empty-state phrasing. 🟢 risks_high set to display:none (no High risks in ER).

14. Monitoring

# Description Result Comments
14.1 The section is derived from the ER Monitoring section 🟢 Derived from ER Monitoring table (lines 371-376).
14.2 All measurable/quantifiable biomarkers from the Monitoring section are listed 🟢 Three quantifiable markers listed (cortisol, glucose/insulin, vitamin D); subjective sleep-onset latency belongs to Qualitative Assessment.
14.3 [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. 🟢 Cadence derived from ER line 369.

15. Qualitative Assessment

# Description Result Comments
15.1 The section is derived from the ER Monitoring section 🟢 Derived from ER qualitative markers (lines 380-384).
15.2 All subjective/qualitative biomarkers from the Monitoring section are listed 🟢 All five ER qualitative markers listed verbatim.

Issues 20/06/2026 02:23

Pass rate 100.00%. No issues found.

Issues 20/06/2026 02:19

  1. 4.2 / 4.3 — Protocol label abbreviated: action_3_label reads “Single vs split dosing” (QRS line 466), abbreviating the ER’s verbatim bold label “Single versus split dosing” (ER line 296); “versus” must not be shortened to “vs”.
  2. 12.3 / 12.4 — PCOS qualifier not stripped: benefits_low retains the parenthetical “(adjunct in PCOS)” (QRS line 528), which is a qualifier/scope note that must be stripped rather than preserved.

Fixes 20/06/2026 02:19

  1. 4.2 / 4.3 — Protocol label de-abbreviated: Restored action_3_label from “Single vs split dosing” to the ER’s verbatim bold label “Single versus split dosing”.
  2. 12.3 / 12.4 — PCOS qualifier stripped: Removed the parenthetical “(adjunct in PCOS)” from benefits_low, leaving “support for metabolic and reproductive health”.